Quantitative assessment of Cerenkov luminescence for radioguided brain tumor resection surgery
نویسندگان
چکیده
منابع مشابه
Cerenkov luminescence imaging (CLI) for image-guided cancer surgery
Cerenkov luminescence imaging (CLI) is a novel molecular optical imaging technique based on the detection of optical Cerenkov photons emitted by positron emission tomography (PET) imaging agents. The ability to use clinically approved tumour-targeted tracers in combination with small-sized imaging equipment makes CLI a particularly interesting technique for image-guided cancer surgery. The past...
متن کاملIntraoperative Assessment of Tumor Resection Margins in Breast-Conserving Surgery Using 18F-FDG Cerenkov Luminescence Imaging: A First-in-Human Feasibility Study.
In early-stage breast cancer, the primary treatment option for most women is breast-conserving surgery (BCS). There is a clear need for more accurate techniques to assess resection margins intraoperatively, because on average 20% of patients require further surgery to achieve clear margins. Cerenkov luminescence imaging (CLI) combines optical and molecular imaging by detecting light emitted by ...
متن کاملEndoscopic imaging of Cerenkov luminescence
We demonstrate feasibility of endoscopic imaging of Cerenkov light originated when charged nuclear particles, emitted from radionuclides, travel through a biological tissue of living subjects at superluminal velocity. The endoscopy imaging system consists of conventional optical fiber bundle/ clinical endoscopes, an optical imaging lens system, and a sensitive low-noise charge coupled device (C...
متن کاملGuidelines for radioguided parathyroid surgery.
OBJECTIVE To confirm or refute the notion that only parathyroid adenomas have radioactivity higher than 20% of background. DESIGN Retrospective analysis of a prospective patient data set. SETTING Tertiary care referral center. PATIENTS Forty-six patients (9 men and 37 women; mean +/- SD age, 53.7 +/- 12.1 years) underwent thyroid and parathyroid surgery between December 2005 and December ...
متن کاملCerenkov luminescence imaging of medical isotopes.
UNLABELLED The development of novel multimodality imaging agents and techniques represents the current frontier of research in the field of medical imaging science. However, the combination of nuclear tomography with optical techniques has yet to be established. Here, we report the use of the inherent optical emissions from the decay of radiopharmaceuticals for Cerenkov luminescence imaging (CL...
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ژورنال
عنوان ژورنال: Physics in Medicine and Biology
سال: 2017
ISSN: 0031-9155,1361-6560
DOI: 10.1088/1361-6560/aa6641